IgE in Host Defense against Bee Venom

While allergic reactions are often associated with discomfort and hassle, researchers from Stanford University have found that they might not be as unnecessary as perceived in the past. More specifically, these scientists argue that an allergic-like immune response might serve as a built-in protection mechanism against toxins in the human body. Their surprising conclusion follows the discovery that bee venom triggers the formation of antibodies known as Immunoglobulin E (IgE) in mice, which serve as a protective shield minimizing the damage caused by increased quantities of venom. This is the first time that the direct protective role of IgEs against venom has been observed, and this discovery suggests that allergies are not entirely unnecessary. Allergies "fight" against microorganisms that threaten health.