Introduction to Conventional Liposomes

Liposomes are the most common and well-studied nanocarriers for targeted drug delivery. They have improved therapies in a series of biomedical applications by stabilizing the therapeutic compounds, overcoming obstacles to cell and tissue uptake, and improving the biodistribution of the compounds at targeted sites in vivo. Combining advanced preparation technologies for various liposomes, Creative Biolabs provides customized services for conventional liposome formulation design and drug encapsulation.

Conventional liposomes are the first generation of liposomes. They are a family of vesicle structures based on a lipid bilayer surrounding aqueous compartments, which can be composed of cationic, anionic or neutral (phosphate) lipids and cholesterol. Conventional liposomes formulations are mainly composed of natural phospholipids or lipids, such as 1,2-distearyl-sn-glycerin-3-phosphatidylcholine (DSPC), sphingomyelin, lecithin and monosialoganglioside.