Early diagnosis of rheumatoid arthritis (RA) can help to identify risk patients, prevent complications and progression, and help patients to recover more quickly. With wealthy experience in the in vitro diagnostic (IVD) immunoassay development, Creative Biolabs is proud to offer one-stop IVD immunoassay and kit development services targeting different biomarkers of RA to improve its early diagnosis.
Introduction to RA
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation and joint damage with a heterogeneous course and different pathogenic mechanisms. It typically manifests with signs of inflammation, with the affected joints being swollen, warm, painful, and stiff. The disease may also affect or damage other parts of the body, including skins, lungs, heart and blood vessels. Multiple genetic and environmental factors have been associated with an increased risk for RA. Of these, the strongest associations have been seen with female sex, a family history of RA, the genetic factor the “shared epitope”, and exposure to tobacco smoke. RA carries a substantial burden for both the individual and society. The individual burden results from musculoskeletal deficits, with an attendant decline in physical function, quality of life, and cumulative comorbid risk. The socioeconomic burden, aside from major direct medical costs, is a consequence of functional disability, reduced work capacity, and decreased societal participation.
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