Drug delivery by vesicular system has overtaken the pre-existing drugs by improving therapeutic efficacy and by sustaining and controlling action. Ethosomes are novel carrier systems used for delivery of drugs possessing low penetration through the biological membrane, mainly skin. With years of experience and high-end technologies in dermal and transdermal drug delivery research, Creative Biolabs has successfully developed a series of innovative and diversified lipid-based drug delivery platforms to provide fast and convenient services for our worldwide customers. Now, we provide high-quality no matter individual ethosomes development services and commercial ethosomes products for our clients to help your project make great progress.
Ethosomes
Ethosomal drug delivery system is non-invasive and delivers the drug to the deep skin layers to the systemic circulation. They are soft, malleable vesicles composed mainly of phospholipids such as phosphatidylserine, phosphatidylcholine, ethanol (relatively high concentration) and water, possessing a wide range of sizes from tens of nanometres to microns. Drug delivery can be modulated by altering alcohol:water ratio. In detail, some preferred phospholipids are soya phospholipids and high concentration of alcohol (20-45%) in the formulation provides soft, flexible characteristics and stability to the vesicles and it also disrupts lipid bilayer structure of the skin results in an increase in the membrane permeability.
